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1

Data analysis in stability studies of biopharmaceutical drugs with isothermal and non-isothermal assays

Alexis Oliva, Matías Llabrés, José B. Fariña

Journal:

TrAC Trends in Analytical Chemistry

Year:

2011

Language:

english

File:

PDF, 671 KB

english, 2011

2

Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: Synthesis, pharmacological evaluation and mechanistic studies

Llabrés, Salomé, García-Ratés, Sara, Cristóbal-Lecina, Edgar, Riera, Antoni, Borrell, José Ignacio, Camarasa, Jorge, Pubill, David, Luque, F. Javier, Escubedo, Elena

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

3

Capability measurement of size-exclusion chromatography with a light-scattering detection method in a stability study of bevacizumab using the process capability indices

Oliva, Alexis, Llabrés, Matías, Fariña, José B.

Journal:

Journal of Chromatography A

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

4

Stability Study of Human Serum Albumin Pharmaceutical Preparations

ALEXIS OLIVA, ANA SANTOVEÑA, MATIAS LLABRES, JOSE B. FARIÑA

Journal:

Journal of Pharmacy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 196 KB

english, 1999

5

MANOVA of statistical moments in biopharmaceutical studies: A numerical example with three equally spaced doses of amoxicillin

José L. Vila, Ramón Martínez, Javier Giménez, Matias Llabrés

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1980

Language:

english

File:

PDF, 502 KB

english, 1980

6

An improved methodology for data analysis in accelerated stability studies of peptide drugs: Practical considerations

Alexis Oliva, José B. Fariña, Matías Llabrés

Journal:

Year:

2012

Language:

english

File:

PDF, 718 KB

english, 2012

7

Quantification of the effect of excipients on bioavailability by means of response surfaces III: In vivo-in vitro correlations

Matías Llabrés, Jose L. Vila, Ramón Martínez-Pacheco

Journal:

Journal of Pharmaceutical Sciences

Year:

1982

Language:

english

File:

PDF, 354 KB

english, 1982

8

Quantification of the effect of excipients on bioavailability by means of response surfaces I: Amoxicillin in fat matrix

Matías Llabrés, José L. Vila, Ramón Martínez-Pacheco

Journal:

Journal of Pharmaceutical Sciences

Year:

1982

Language:

english

File:

PDF, 455 KB

english, 1982

9

Quantification of the effect of excipients on bioavailability by means of response surfaces II: Amoxicillin in fat-silica matrix

Matías Llabrés, José L. Vila, Ramón Martínez-Pacheco

Journal:

Journal of Pharmaceutical Sciences

Year:

1982

Language:

english

File:

PDF, 403 KB

english, 1982

10

Dubiusine from Narcissus dubius

Jaume Bastida, Jose M. Llabres, Francesc Viladomat, Carles Codina, Mario Rubiralta, Miguel Feliz

Journal:

Year:

1988

Language:

english

File:

PDF, 270 KB

english, 1988

11

hGH release from directly compressed hGH-PLGA biodegradable implantable tablets: Influence of physicomechanical factors

Ana Santoveña, Carmen Alvarez-Lorenzo, Matias Llabrés, Angel Concheiro, Jose B. Fariña

Journal:

European Polymer Journal

Year:

2009

Language:

english

File:

PDF, 706 KB

english, 2009

12

Measurement of uncertainty in peptide molecular weight determination using size-exclusion chromatography with multi-angle laser light-scattering detection and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Alexis Oliva, José B. Fariña, Matı́as Llabrés

Journal:

Analytica Chimica Acta

Year:

2004

Language:

english

File:

PDF, 125 KB

english, 2004

13

Application of a validated stability-indicating chromatographic method to evaluate the reproducibility between batches of small peptides in solution

Alexis Oliva, Matías Llabrés, José B. Fariña

Journal:

Analytica Chimica Acta

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

14

Characterization and photo-Fenton treatment of used tires leachate

Judith Sarasa, Tomás Llabrés, Peña Ormad, Rosa Mosteo, José Luis Ovelleiro

Journal:

Journal of Hazardous Materials

Year:

2006

Language:

english

File:

PDF, 319 KB

english, 2006

15

Evaluation of non-isothermal methods in stability studies of human insulin pharmaceutical preparations

Alexis Oliva, Marta Suárez, Juan Ramón Hernández, Matías Llabrés, José B. Fariña

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2009

Language:

english

File:

PDF, 652 KB

english, 2009

16

Two alkaloids from Narcissus requienii

José M. Llabrés, Francesc Viladomat, Jaume Bastida, Carles Codina, Manuel Serrano, Mario Rubiralta, Miguel Feliz

Journal:

Year:

1986

Language:

english

File:

PDF, 409 KB

english, 1986

17

Alkaloids from Narcissus confusus

Jaume Bastida, Francesc Viladomat, Jose M. Llabres, Carles Codina, Miguel Feliz, Mario Rubiralta

Journal:

Year:

1987

Language:

english

File:

PDF, 583 KB

english, 1987

18

Phenanthridine alkaloids from Narcissus assoanus

José M. Llabrés, Francesc Viladomat, Jaume Bastida, Carles Codina, Mario Rubiralta

Journal:

Year:

1986

Language:

english

File:

PDF, 214 KB

english, 1986

19

Biodegradable laminar implants for sustained release of recombinant human growth hormone

Juan T Garcı́a, Mª Jesús Dorta, Obdulia Munguı́a, Matı́as Llabrés, José B Fariña

Journal:

Year:

2002

Language:

english

File:

PDF, 117 KB

english, 2002

20

Development of two high-performance liquid chromatographic methods for the analysis and characterization of insulin and its degradation products in pharmaceutical preparations

Alexis Oliva, José Fariña, Matı́as Llabrés

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 235 KB

english, 2000

21

Chromatographic characterization of synthetic peptides: SPf66 malaria vaccine

Ana Santoveña, Alexis Oliva, Fanny Guzman, Manuel E. Patarroyo, Matı́as Llabrés, José B. Fariña

Journal:

Journal of Chromatography B

Year:

2002

Language:

english

File:

PDF, 128 KB

english, 2002

22

Statistical assessment of between batch stability equivalence

Matı́as Llabrés, Alexis Oliva, José Fariña

Journal:

International Journal of Pharmaceutics

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

23

Potential applications of PLGA film-implants in modulating in vitro drugs release

Marı́a Jesús Dorta, Ana Santoveña, Matı́as Llabrés, José B Fariña

Journal:

International Journal of Pharmaceutics

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

24

Comparative study of protein molecular weights by size-exclusion chromatography and laser-light scattering

Alexis Oliva, Matı́as Llabrés, José B Fariña

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2001

Language:

english

File:

PDF, 118 KB

english, 2001

25

Effect of high shear rate on stability of proteins: kinetic study

Alexis Oliva, Ana Santoveña, José Fariña, Matı́as Llabrés

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

26

Data Analysis of Kinetic Modelling Used in Drug Stability Studies: IsothermalVersusNonisothermal Assays

Alexis Oliva, Matías Llabrés, José B. Fariña

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 267 KB

english, 2006

27

Anti-tumor effects of adenovirus containing human growth hormone sequences in a mouse model of human ovarian cancer

Yonglian Zhu, José B. Fariña, Syrus Meshack, Ana Santoveña, Shilpa Patel, Alexis Oliva, Matias Llabrés, Michael E. Hodsdon, Carmen J. Booth, Priscilla S. Dannies

Journal:

Endocrine (Springer)

Year:

2010

Language:

english

File:

PDF, 594 KB

english, 2010

28

Pharmacokinetics analysis of sustained release hGH biodegradable implantable tablets using a mouse model of human ovarian cancer

Ana Santoveña, José B. Fariña, Matías Llabrés, Yonglian Zhu, Priscilla Dannies

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 507 KB

english, 2010

29

Ontogenic variations in the alkaloids of Narcissus assoanus

Francesc Viladomat, José M. Llabrés, Jaume Bastida, Rosa M. Cusidó, Carles Codina

Journal:

Physiologia Plantarum

Year:

1986

Language:

english

File:

PDF, 337 KB

english, 1986

30

In-vitro release of fluoropyrimidines from PLGA film implants

M. Jesús Dorta, Alexis Oliva, Obdulia Munguía, Matías Llabrés, José B. Fariña

Journal:

Journal of Pharmacy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 191 KB

english, 2002

31

Optimization of dl-PLA molecular weight via the response surface method

Obdulia Munguia, Araceli Delgado, José Fariña, Carmen Evora, Matías Llabres

Journal:

International Journal of Pharmaceutics

Year:

1992

Language:

english

File:

PDF, 313 KB

english, 1992

32

Solid-state stability studies of cholecystokinin (CCK-4) peptide under nonisothermal conditions using thermal analysis, chromatography and mass spectrometry

Alexis Oliva, David Sánchez Ashen, Mario Salmona, José B. Fariña, Matías Llabrés

Journal:

European Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 439 KB

english, 2010

33

Application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and hydrogen exchange combined with enzymatic digestion for the structural characterization of antimalaric Spf66 peptide

Alexis Oliva, Matías Llabrés, José B. Fariña

Journal:

Year:

2007

Language:

english

File:

PDF, 347 KB

english, 2007

34

Estimation of uncertainty in size-exclusion chromatography with a double detection system (light-scattering and refractive index)

Alexis Oliva, Matías Llabrés, José B. Fariña

Journal:

Year:

2009

Language:

english

File:

PDF, 510 KB

english, 2009

35

Single-Molecule Spectroscopy Reveals the Conformational Heterogeneity of Conducting Polymers Encapsulated within Hollow Silica Spheres

Peris, Encarna, Hernando, Jordi, Llabrés i Xamena, Francesc X., van Hulst, Niek F., Bourdelande, José L., García, Hermenegildo

Journal:

The Journal of Physical Chemistry C

Year:

2008

Language:

english

File:

PDF, 418 KB

english, 2008

36

Development and validation of an UPLC method for determination of content uniformity in low-dose solid drugs products using the design space approach

Oliva, Alexis, Fariña, José B., Llabrés, Matías

Journal:

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

37

Narcissus Alkaloids, VIII. Mesembrenone: An Unexpected Alkaloid From Narcissus Pallidulus

Bastida, Jaume, Viladomat, Francesc, Llabres, Jose Manuel, Ramirez, Guillermo, Codina, Carles, Rubiralta, Mario

Journal:

Journal of Natural Products

Year:

1989

Language:

english

File:

PDF, 198 KB

english, 1989

38

Narcissus Alkaloids, III. 9-O-Demethylhomolycorine from Narcissus confusus

Bastida, Jaume, Llabrés, Jose M., Viladomat, Francesc, Codina, Carles, Rubiralta, Mario, Feliz, Miguel

Journal:

Journal of Natural Products

Year:

1987

Language:

english

File:

PDF, 238 KB

english, 1987

39

Proton Transport through Robust CPO-27-type Metal Organic Frameworks

Solís, Cecilia, Palaci, Daniel, Llabrés i Xamena, Francesc X., Serra, José M.

Journal:

The Journal of Physical Chemistry C

Year:

2014

Language:

english

File:

PDF, 3.18 MB

english, 2014

40

N.M.R. and conformational analysis of some Te-containing ortho-substituted benzaldehydes

Baiwir, Marcel, Llabres, Gabriel, Denoel, José, Piette, Jean-Louis

Journal:

Molecular Physics

Year:

1973

Language:

english

File:

PDF, 371 KB

english, 1973

41

Etude par résonance magnétique nucléaire de composés organiques contenant des chalcogènes. I. L'anisole et ses analogues soufré, sélénié et tellure

Llabres, Gabriel, Baiwir, Marcel, Christiaens, Léon, Denoel, José, Laitem, Léopold, Piette, Jean-Louis

Journal:

Canadian Journal of Chemistry

Year:

1978

File:

PDF, 263 KB

1978

42

Comparison of Shelf-Life Estimates for a Human Insulin Pharmaceutical Preparation Using the Matrix and Full-Testing Approaches

Oliva, Alexis, Fariña, José, Llabrés, Matías

Journal:

Drug Development and Industrial Pharmacy

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

43

Fitting bevacizumab aggregation kinetic data with the Finke–Watzky two-step model: Effect of thermal and mechanical stress

Oliva, Alexis, Llabrés, Matías, Fariña, José B.

Journal:

European Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 880 KB

english, 2015

44

Phytoplankton biovolume is independent from the slope of the size spectrum in the oligotrophic Atlantic Ocean

Moreno-Ostos, Enrique, Blanco, José María, Agustí, Susana, Lubián, Luis M., Rodríguez, Valeriano, Palomino, Roberto L., Llabrés, Moira, Rodríguez, Jaime

Journal:

Journal of Marine Systems

Year:

2015

Language:

english

File:

PDF, 1.60 MB

english, 2015

45

Pre-study and in-study validation of a size-exclusion chromatography method with different detection modes for the analysis of monoclonal antibody aggregates

Oliva, Alexis, Fariña, Jose B., Llabrés, Matías

Journal:

Journal of Chromatography B

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

46

Bifid Condyle: Review of the Literature of the Last 10 Years and Report of Two Cases

López-López, José, Ayuso-Montero, Raúl, Jané Salas, Enric, Roselló-Llabrés, Xavier

Journal:

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

47

New Trends in Analysis of Biopharmaceutical Products

Oliva, Alexis, Farina, Jose, Llabres, Matias

Journal:

Current Pharmaceutical Analysis

Year:

2007

Language:

english

File:

PDF, 595 KB

english, 2007

48

Development of an ultra high performance liquid chromatography method for determining triamcinolone acetonide in hydrogels using the design of experiments/design space strategy in combination with process capability index

Oliva, Alexis, Monzón, Cecilia, Santoveña, Ana, Fariña, José B., Llabrés, Matías

Journal:

Journal of Separation Science

Year:

2016

Language:

english

File:

PDF, 666 KB

english, 2016

49

Influence of Anthropometric Characteristics in Patients With Her2-Positive Breast Cancer on Initial Plasma Concentrations of Trastuzumab

González García, Jonathan, Gutiérrez Nicolás, Fernando, Nazco Casariego, Gloria Julia, Batista López, José Norberto, Ceballos Lenza, Isaac, Ramos Díaz, Ruth, Llabrés Martínez, Matías

Journal:

Annals of Pharmacotherapy

Year:

2017

Language:

english

File:

PDF, 537 KB

english, 2017

50

Synthesis, Optical Properties, and DNA Interaction of New Diquats Based on Triazolopyridines and Triazoloquinolines

Llabres-Campaner, Pedro J., Guijarro, Lluís, Giarratano, Claudia, Ballesteros-Garrido, Rafael, Zaragozá, Ramón J., Aurell, M. José, García-España, Enrique, Ballesteros, Rafael, Abarca, Belén

Journal:

Chemistry - A European Journal

Year:

2017

Language:

english

File:

PDF, 935 KB

english, 2017

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